Ontology highlight
ABSTRACT:
SUBMITTER: Vera IM
PROVIDER: S-EPMC6975259 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Vera Iset Medina IM Grilo Ruivo Margarida T MT Lemos Rocha Leonardo F LF Marques Sofia S Bhatia Sangeeta N SN Mota Maria M MM Mancio-Silva Liliana L
JCI insight 20191219 24
Despite an unprecedented 2 decades of success, the combat against malaria - the mosquito-transmitted disease caused by Plasmodium parasites - is no longer progressing. Efforts toward eradication are threatened by the lack of an effective vaccine and a rise in antiparasite drug resistance. Alternative approaches are urgently needed. Repurposing of available, approved drugs with distinct modes of action are being considered as viable and immediate adjuncts to standard antimicrobial treatment. Such ...[more]