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Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration.

ABSTRACT: A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.

SUBMITTER: Soares L

PROVIDER: S-EPMC6982736 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Detection of the Crystallization Process of Paracetamol with a Multi-Mode Optical Fiber in a Reflective Configuration.

Soares Liliana L Novais Susana S Ferreira António A Frazão Orlando O Silva Susana S

Sensors (Basel, Switzerland) 20191222 1

A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% <i>v</i>/<i>v</i> of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time. ...[more]

PMID: 31877833

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