Ontology highlight
ABSTRACT:
SUBMITTER: Yin YJ
PROVIDER: S-EPMC6983046 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Yin Yan-Jiao YJ Huang Dan-Ling DL Qiu Bin B Cai Dan D Zhang Jiao-Jiao JJ Wang Shao-Xiang SX Qin Da-Peng DP Cheng Yong-Xian YX
Molecules (Basel, Switzerland) 20191231 1
Five new meroterpenoids, zizhines P-S and U (<b>1</b>-<b>4</b>,<b>7</b>), together with two known meroterpenoids (<b>5</b> and <b>6</b>) were isolated from <i>Ganoderma sinensis</i>. Their structures including absolute configurations were assigned by using spectroscopic, computational, and chemical methods. Racemics zizhines P and Q were purified by HPLC on chiral phase. Biological evaluation found that <b>4</b>, <b>5</b> and <b>6</b> are cytotoxic toward human cancer cells (A549, BGC-823, Kyse3 ...[more]