Ontology highlight
ABSTRACT:
SUBMITTER: Yang JH
PROVIDER: S-EPMC6983056 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Yang Jing-Hua JH Wang Xin-Yi XY Zhou Yi-Ping YP Lu Rong R Chen Chin-Ho CH Zhang Meng-Han MH Cheng Yung-Yi YY Morris-Natschke Susan L SL Lee Kuo-Hsiung KH Wang Yun-Song YS
Molecules (Basel, Switzerland) 20191226 1
Two new carbazole alkaloids (<b>1</b>,<b>2</b>) and six known carbazole alkaloids (<b>3</b>-<b>8</b>) were isolated from <i>Clausena anisum-olens</i>. Their structures were elucidated based on extensive spectroscopic analysis. All isolated compounds (<b>1</b>-<b>8</b>) were evaluated for their anti-HIV effects on virus replication in MT-4 lymphocytes infected by HIV-1<sub>NL4-3</sub> Nanoluc-sec virus, and new carbazole alkaloid <b>1</b> exhibited anti-HIV activity with an EC<sub>50</sub> value ...[more]