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ABSTRACT:
SUBMITTER: Lee JS
PROVIDER: S-EPMC6995602 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Lee Jin Su JS Jeong Miran M Park Sangsu S Ryu Seung Mok SM Lee Jun J Song Ziteng Z Guo Yuanqiang Y Choi Jung-Hye JH Lee Dongho D Jang Dae Sik DS
Biomolecules 20191129 12
Two new aryltetralin lactone lignans, petasitesins A and B were isolated from the hot water extract of the leaves of butterbur (<i>Petasites japonicus</i>) along with six known compounds. The chemical structures of lignans <b>1</b> and <b>2</b> were elucidated on the basis of 1D and 2D nuclear magnetic resonance (NMR) spectroscopic data, electronic circular dichroism (ECD) and vibrational circular dichroism (VCD) spectra. Petasitesin A and cimicifugic acid D showed significant inhibitory effects ...[more]