Ontology highlight
ABSTRACT:
SUBMITTER: Binh MT
PROVIDER: S-EPMC7029004 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Binh Mai Thanh MT Hoan Nghiem Xuan NX Giang Dao Phuong DP Tong Hoang Van HV Bock C-Thomas CT Wedemeyer Heiner H Toan Nguyen Linh NL Bang Mai Hong MH Kremsner Peter G PG Meyer Christian G CG Song Le Huu LH Velavan Thirumalaisamy P TP
Scientific reports 20200218 1
SMYD3 (SET and MYND domain-containing protein 3) is involved in histone modification, which initiates oncogenesis by activating transcription of multiple downstream genes. To investigate associations of variable numbers of tandem repeats (VNTR) variants in the SMYD3 gene promoter, SMYD3 serum levels and SMYD3 mRNA expression in hepatitis B virus (HBV) infection and clinical progression of related liver disease. SMYD3 VNTRs were genotyped in 756 HBV patients and 297 healthy controls. SMYD3 serum ...[more]