Ontology highlight
ABSTRACT:
SUBMITTER: Rodius S
PROVIDER: S-EPMC7031222 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Rodius Sophie S de Klein Niek N Jeanty Céline C Sánchez-Iranzo Héctor H Crespo Isaac I Ibberson Mark M Xenarios Ioannis I Dittmar Gunnar G Mercader Nadia N Niclou Simone P SP Azuaje Francisco F
Scientific reports 20200219 1
Myocardial infarction (MI) is a leading cause of death worldwide. Reperfusion is considered as an optimal therapy following cardiac ischemia. However, the promotion of a rapid elevation of O<sub>2</sub> levels in ischemic cells produces high amounts of reactive oxygen species (ROS) leading to myocardial tissue injury. This phenomenon is called ischemia reperfusion injury (IRI). We aimed at identifying new and effective compounds to treat MI and minimize IRI. We previously studied heart regenerat ...[more]