Ontology highlight
ABSTRACT:
SUBMITTER: Shao G
PROVIDER: S-EPMC7031931 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Shao Gaohai G Liu Qingjun Q Yang Ling L Feng Guibo G Zhao Wang W Huang Zhongyan Z Yang Zhao Z
Journal of inflammation (London, England) 20200219
<h4>Background</h4>Prediction and identification of cytotoxic T lymphocyte (CTL) epitopes from tumor associated antigens is a crucial step for the development of tumor immunotherapy strategy. Endocan has been identified as antigen overexpressed in various tumors.<h4>Methods</h4>In this experiment, we predicted and identified HLA-A2-restricted CTL epitopes from endocan by using the following procedures. Firstly, we predicted the epitopes from the amino acid sequence of endocan by computer-based m ...[more]