Ontology highlight
ABSTRACT:
SUBMITTER: Abbott J
PROVIDER: S-EPMC7035150 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Abbott Jeffrey J Ye Tianyang T Krenek Keith K Gertner Rona S RS Ban Steven S Kim Youbin Y Qin Ling L Wu Wenxuan W Park Hongkun H Ham Donhee D
Nature biomedical engineering 20190923 2
Current electrophysiological or optical techniques cannot reliably perform simultaneous intracellular recordings from more than a few tens of neurons. Here we report a nanoelectrode array that can simultaneously obtain intracellular recordings from thousands of connected mammalian neurons in vitro. The array consists of 4,096 platinum-black electrodes with nanoscale roughness fabricated on top of a silicon chip that monolithically integrates 4,096 microscale amplifiers, configurable into pseudoc ...[more]