Ontology highlight
ABSTRACT:
SUBMITTER: Malone JA
PROVIDER: S-EPMC7055494 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Organic letters 20190429 10
An expedient synthesis of tetrahydroindoles and tetrahydrocyclopenta[ b]pyrroles, highlighted by Brønsted acid catalyzed formal [2 + 2 + 1] annulation reaction, is reported. Using three readily accessible reaction components, i.e., an electrophilic species in silyloxyallyl cations and two distinct nucleophiles in silylenol ethers and amines, our chemistry enables the assembly and functionalization of these biologically important N-heterocycles in a highly modular manner. ...[more]