Ontology highlight
ABSTRACT:
SUBMITTER: Chojnowski G
PROVIDER: S-EPMC7057216 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chojnowski Grzegorz G Choudhury Koushik K Heuser Philipp P Sobolev Egor E Pereira Joana J Oezugurel Umut U Lamzin Victor S VS
Acta crystallographica. Section D, Structural biology 20200228 Pt 3
The performance of automated protein model building usually decreases with resolution, mainly owing to the lower information content of the experimental data. This calls for a more elaborate use of the available structural information about macromolecules. Here, a new method is presented that uses structural homologues to improve the quality of protein models automatically constructed using ARP/wARP. The method uses local structural similarity between deposited models and the model being built, ...[more]