Ontology highlight
ABSTRACT:
SUBMITTER: Ravenhill BJ
PROVIDER: S-EPMC7067879 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20200312 1
Monocytes are a critical component of the cellular innate immune system, and can be subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and CD16 expression. Classical monocytes play the canonical role of phagocytosis, and account for the majority of circulating cells. Intermediate and non-classical cells are known to exhibit varying levels of phagocytosis and cytokine secretion, and are differentially expanded in certain pathological states. Characteris ...[more]