Ontology highlight
ABSTRACT:
SUBMITTER: Riboni L
PROVIDER: S-EPMC7072483 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Riboni Laura L Abdel Hadi Loubna L Navone Stefania Elena SE Guarnaccia Laura L Campanella Rolando R Marfia Giovanni G
Cells 20200201 2
As a key hub of malignant properties, the cancer microenvironment plays a crucial role intimately connected to tumor properties. Accumulating evidence supports that the lysophospholipid sphingosine-1-phosphate acts as a key signal in the cancer extracellular milieu. In this review, we have a particular focus on glioblastoma, representative of a highly aggressive and deleterious neoplasm in humans. First, we highlight recent advances and emerging concepts for how tumor cells and different recruit ...[more]