Ontology highlight
ABSTRACT:
SUBMITTER: Grenier MC
PROVIDER: S-EPMC7074219 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Grenier Melissa C MC Ding Shilei S Vézina Dani D Chapleau Jean-Philippe JP Tolbert William D WD Sherburn Rebekah R Schön Arne A Somisetti Sambasivarao S Abrams Cameron F CF Pazgier Marzena M Finzi Andrés A Smith Amos B AB
ACS medicinal chemistry letters 20191115 3
With approximately 37 million people living with HIV worldwide and an estimated 2 million new infections reported each year, the need to derive novel strategies aimed at eradicating HIV-1 infection remains a critical worldwide challenge. One potential strategy would involve eliminating infected cells via antibody-dependent cellular cytotoxicity (ADCC). HIV-1 has evolved sophisticated mechanisms to conceal epitopes located in its envelope glycoprotein (Env) that are recognized by ADCC-mediating a ...[more]