Ontology highlight
ABSTRACT:
SUBMITTER: Lee Y
PROVIDER: S-EPMC7076458 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Lee Yechan Y Kumar Sujeet S Kim Sou Hyun SH Seong Keum-Yong KY Lee Hyeseon H Kim Chaerin C Jung Young-Suk YS Yang Seung Yun SY
Pharmaceutics 20200127 2
Glutathione is a natural anti-aging substance that prevents the oxidation of protein thiols from reactive oxygen species. In the pharmaceutical industry, reduced glutathione (GSH) has been widely used for skin whitening due to its ability to inhibit tyrosinase. However, its poor permeability and foul odor limit its use in skin applications. Herein, we report a GSH-loaded dissolving microneedle (MN) patch prepared with hyaluronic acid (HA) that enables enhanced permeation across the skin and redu ...[more]