Ontology highlight
ABSTRACT:
SUBMITTER: Runeberg PA
PROVIDER: S-EPMC7076729 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Organic letters 20190926 20
Aerobic Pd(AcO)<sub>2</sub>/pyridine-catalyzed oxidation of unprotected carbohydrate-based terminal alkenes was studied. In accordance with previous reports, the initial reaction step gave methyl ketones. However, our substrates partially gave subsequent α,β-water elimination and alcohol oxidation to α,β-unsaturated 2,5-diketones. Upon increasing the pressure of O<sub>2</sub>, the reaction was shifted toward formation of α,β-epoxy-2-ketones. The reactions were stereoselective and gave up to quan ...[more]