Dataset Information
Efficient synthesis of ?'-amino-?,?-unsaturated ketones.
Ontology highlight
ABSTRACT:
SUBMITTER: Abrunhosa-Thomas I
PROVIDER: S-EPMC3596044 | biostudies-other | 2013
REPOSITORIES: biostudies-other
Publications
Efficient synthesis of β'-amino-α,β-unsaturated ketones.
Beilstein journal of organic chemistry 20130306
A general and simple procedure to access chiral β'-amino-α,β-enones, in seven steps, from an α,β unsaturated ester has been described. The use of a Horner-Wadsworth-Emmons reaction as a key step for generating the β'-amino-α,β-enones, permits access to a range of substrates under mild conditions and in moderate to high yield. ...[more]