Ontology highlight
ABSTRACT:
SUBMITTER: Guo Q
PROVIDER: S-EPMC7081228 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Nature communications 20200319 1
The C-N cross coupling reaction has always been a fundamental task in organic synthesis. However, the direct use of N-H group of aryl amines to generate N-centered radicals which would couple with alkyl radicals to construct C-N bonds is still rare. Here we report a visible light-promoted C-N radical cross coupling for regioselective amination of remote C(sp<sup>3</sup>)-H bonds. Under visible light irradiation, the N-H groups of aryl amines are converted to N-centered radicals, and are then tra ...[more]