Ontology highlight
ABSTRACT:
SUBMITTER: Zhou ZF
PROVIDER: S-EPMC7086007 | biostudies-literature | 2020 Mar.
REPOSITORIES: biostudies-literature
Zhou Zhi-Feng ZF Jiang Lei L Zhao Qing Q Wang Yu Y Zhou Jing J Chen Qin-Kai QK Lv Jin-Lei JL
Journal of Zhejiang University. Science. B 20200301 3
Diabetic nephropathy (DN) is currently the most common complication of diabetes. It is considered to be one of the leading causes of end-stage renal disease (ESRD) and affects many diabetic patients. The pathogenesis of DN is extremely complex and has not yet been clarified; however, in recent years, increasing evidence has shown the important role of innate immunity in DN pathogenesis. Pattern recognition receptors (PRRs) are important components of the innate immune system and have a significa ...[more]