Ontology highlight
ABSTRACT:
SUBMITTER: Eitzinger A
PROVIDER: S-EPMC7091536 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Eitzinger Andreas A Mayer Robert J RJ Hampel Nathalie N Mayer Peter P Waser Mario M Ofial Armin R AR
Organic letters 20200302 6
The electrophilic reactivity of a series of 8-arylated vinyl <i>p</i>-quinone methides (<i>p</i>VQMs) was determined by analyzing the kinetics of their reactions with carbanions in DMSO at 20 °C according to the linear free energy relationship log <i>k</i> = s<sub>N</sub>(<i>N</i> + <i>E</i>). The electrophilicity parameters <i>E</i> for <i>p</i>VQMs were used to successfully predict Michael-additions with structurally diverse C-, N-, S-, and H-nucleophiles. ...[more]