Ontology highlight
ABSTRACT:
SUBMITTER: van den Broek B
PROVIDER: S-EPMC7098274 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
van den Broek Bryan B van der Flier Michiel M de Groot Ronald R de Jonge Marien I MI Langereis Jeroen D JD
Journal of innate immunity 20190703 2
Streptococcus pneumoniae and Neisseria meningitidis are pathogens that frequently colonize the nasopharynx in an asymptomatic manner but are also a cause of invasive bacterial infections mainly in young children. The complement system plays a crucial role in humoral immunity, complementing the ability of antibodies to clear microbes, thereby protecting the host against bacterial infections, including S. pneumoniae and N. meningitidis. While it is widely accepted that complement deficiencies due ...[more]