Ontology highlight
ABSTRACT:
SUBMITTER: Belviso I
PROVIDER: S-EPMC7099865 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Belviso Immacolata I Romano Veronica V Sacco Anna Maria AM Ricci Giulia G Massai Diana D Cammarota Marcella M Catizone Angiolina A Schiraldi Chiara C Nurzynska Daria D Terzini Mara M Aldieri Alessandra A Serino Gianpaolo G Schonauer Fabrizio F Sirico Felice F D'Andrea Francesco F Montagnani Stefania S Di Meglio Franca F Castaldo Clotilde C
Frontiers in bioengineering and biotechnology 20200320
The complex and highly organized environment in which cells reside consists primarily of the extracellular matrix (ECM) that delivers biological signals and physical stimuli to resident cells. In the native myocardium, the ECM contributes to both heart compliance and cardiomyocyte maturation and function. Thus, myocardium regeneration cannot be accomplished if cardiac ECM is not restored. We hypothesize that decellularized human skin might make an easily accessible and viable alternate biologica ...[more]