Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours.
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ABSTRACT:
SUBMITTER: Xu F
PROVIDER: S-EPMC7110906 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Roles of the PI3K/AKT/mTOR signalling pathways in neurodegenerative diseases and tumours.
Xu Fei F Na Lixin L Li Yanfei Y Chen Linjun L
Cell & bioscience 20200401 1
The PI3 K/AKT/mTOR signalling pathway plays an important role in the regulation of signal transduction and biological processes such as cell proliferation, apoptosis, metabolism and angiogenesis. Compared with those of other signalling pathways, the components of the PI3K/AKT/mTOR signalling pathway are complicated. The regulatory mechanisms and biological functions of the PI3K/AKT/mTOR signalling pathway are important in many human diseases, including ischaemic brain injury, neurodegenerative d ...[more]
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