Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC7114436 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Wang Jianzhong J Cong Yanlong Y Yin Renfu R Feng Na N Yang Songtao S Xia Xianzhu X Xiao Yueqiang Y Wang Wenxiu W Liu Xiufan X Hu Shunlin S Ding Chan C Yu Shengqing S Wang Chunfeng C Ding Zhuang Z
Virus research 20150413
Newcastle disease virus (NDV) and Goose parvovirus (GPV) are considered to be two of the most important and widespread viruses infecting geese. In this study, we generated a recombinant rmNA-VP3, expressing GPV VP3 using a modified goose-origin NDV NA-1 by changing the multi-basic cleavage site motif RRQKR↓F of the F protein to the dibasic motif GRQGR↓L as that of the avirulent strain LaSota as a vaccine vector. Expression of the VP3 protein in rmNA-VP3 infected cells was detected by immunofluor ...[more]