Ontology highlight
ABSTRACT:
SUBMITTER: Weiss AKH
PROVIDER: S-EPMC7116474 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Mechanisms of ageing and development 20200620
Fumarylacetoacetate hydrolase (FAH) superfamily members are commonly expressed in the prokaryotic kingdom, where they take part in the committing steps of degradation pathways of complex carbon sources. Besides FAH itself, the only described FAH superfamily members in the eukaryotic kingdom are fumarylacetoacetate hydrolase domain containing proteins (FAHD) 1 and 2, that have been a focus of recent work in aging research. Here, we provide a review of current knowledge on FAHD proteins. Of those, ...[more]