Ontology highlight
ABSTRACT:
SUBMITTER: Lu Y
PROVIDER: S-EPMC7127048 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Lu Yanfang Y Hou Hongyan H Wang Feng F Qiao Long L Wang Xiong X Yu Jing J Liu Weiyong W Sun Ziyong Z
Virology 20160527
Enterovirus 71 (EV71) infection can cause severe diseases, and is becoming increasingly common in children. In the current study, we carried out yeast two-hybrid assays to screen human proteins that could interact with 3A protein of EV71. Human β3 subunit of Na(+)/K(+)-ATPase (ATP1B3) protein was demonstrated to interact with the 3A protein of EV71. Although 3A protein had no effect on the expression of ATP1B3, EV71 infection resulted in elevated expression of ATP1B3 in RD cell line, both on mes ...[more]