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Modified toothpaste application using prepared toothpaste delivering technique increases interproximal fluoride toothpaste delivery.

ABSTRACT: OBJECTIVES:We devised a "prepared toothpaste delivering technique" (PTD technique), a modified the application of toothpaste method for using fluoride toothpaste more effectively. This study aimed to investigate the change in viscosity and fluoride intake into hydroxyapatite of a toothpaste, and deliverability of fluoride toothpaste to the interproximal site with the PTD technique using an interproximal model. METHODS:Eight toothpaste samples were prepared at the following concentrations: ×1.00, ×1.25, ×1.50, ×1.75, ×2.00, ×3.00, ×4.00, and ×5.00. Viscosity of the toothpaste was measured by a Type-B viscometer. Dissolution rate of toothpaste and fluoride uptake into the hydroxy apatite pellet were analyzed by a fluoride selective electrode. Application paste volume and delivery rate was measured using interproximal model and image analysis software during using a finger brush front (FBF), finger brush back (FBB), and toothbrush. RESULTS:As the dilution ratio increased, the viscosity of the toothpaste decreased sharply, F uptake decreased, and dissolution rate increased. F uptake was significantly reduced when the toothpaste was diluted more than 1.75 times. Therefore, in order to improve the effectiveness of the fluoride toothpaste, it is important to deliver the toothpaste to interproximal areas and pit clefts at low dilution. It was observed that PTD technique can be effectively implemented by the finger brush. CONCLUSIONS:The use of a FBF surface in the analysis of an acrylic interproximal model could aid in applying pressure while blocking the space of the groove and preventing outflow of the toothpaste. It was considered that the PTD technique would improve the effects of the fluoride toothpaste, especially in the interproximal site.

SUBMITTER: Satou R

PROVIDER: S-EPMC7133740 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Modified toothpaste application using prepared toothpaste delivering technique increases interproximal fluoride toothpaste delivery.

Satou Ryouichi R Suzuki Seitaro S Takayanagi Atsushi A Yamagishi Atsushi A Sugihara Naoki N

Clinical and experimental dental research 20191212 2

<h4>Objectives</h4>We devised a "prepared toothpaste delivering technique" (PTD technique), a modified the application of toothpaste method for using fluoride toothpaste more effectively. This study aimed to investigate the change in viscosity and fluoride intake into hydroxyapatite of a toothpaste, and deliverability of fluoride toothpaste to the interproximal site with the PTD technique using an interproximal model.<h4>Methods</h4>Eight toothpaste samples were prepared at the following concent ...[more]

PMID: 32250568

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Project description:BackgroundModern toothbrushes origin can be traced to plant-derived chewing sticks, which were documented to be used Babylonians as early as 3500 BC. Chewing sticks are routinely used for cleaning teeth in Asia, Africa, South America, and the Middle East. The aim of the current study was to evaluate the antibacterial effect of miswak herbal toothpaste compared to fluoride toothpaste using a normal toothbrush, against Streptococcus mutans in high caries risk patients.Material and methodsA total of 32 participants were recruited to the current clinical trial using convenience sampling randomly either to miswak or fluoride toothpastes groups (n=16). The bacterial count represented as colony-forming units per milliliter (CFU/ml) was assessed at baseline and after 1 week, 1 month and 3 months. Moreover, the ion release for silicone, calcium, phosphorus, and fluoride from both toothpastes was analyzed in addition to the pH of both toothpastes and their supernatants. Intergroup comparison was performed using independent t test, while intragroup comparison was performed using repeated measures ANOVA followed by tukey post-hoc test and paired t test when appropriate.ResultsThere was no statistically significant difference between both toothpastes for the S. mutans count within each follow up period, however the bacterial count significantly decreased over time in both groups. Signal Fluoride toothpaste exhibited statistically significant higher ion release when compared to the Dabur Miswak toothpaste. There was no statistically significant difference between either toothpastes regarding pH (P = 0.5368), while comparison between supernatants of toothpastes have shown statistically significant difference (P = 0.0194), with a higher pH in miswak toothpaste.ConclusionsMiswak herbal toothpaste possesses a potent antibacterial effect, yet its remineralization potential is questionable due to its inferior ion release that will affect the ion substantivity in saliva, which is an important factor in remineralization. Key words:High caries risk, Miswak, Fluoride, Antibacterial, Streptococcus mutans.

Project description:BackgroundGingivitis is driven by plaque accumulation and, if left untreated, can progress to irreversible periodontitis. For many, the mechanical action of toothbrushing does not achieve adequate plaque control. The aim of this study was to investigate whether twice-daily use of a toothpaste containing 0.2% high molecular weight (HMW) sodium hyaluronate with 67% sodium bicarbonate and 0.221% sodium fluoride (experimental toothpaste) could improve gingival health compared with a regular fluoride toothpaste (negative control). The study also assessed whether the experimental toothpaste could provide additive gingival health benefit over a toothpaste containing only 67% sodium bicarbonate and 0.221% sodium fluoride (positive control).MethodsThis was a single-center, examiner-blinded, randomized, clinical study in healthy adults with mild-to-moderate gingivitis. At baseline, after abstaining from toothbrushing for 12 h, prospective participants underwent oral soft tissue (OST) and oral hard tissue examination followed by assessments for gingival inflammation (Modified Gingival Index [MGI]), gingival bleeding (Bleeding Index [BI]), and supra-gingival plaque (Turesky Plaque Index [TPI]). Eligible participants were stratified by gender and baseline number of bleeding sites (low: <45; high: ≥45 bleeding sites). Following randomization, participants underwent prophylactic dental treatment. Participants received a full OST examination, MGI, BI and TPI assessments after 3 days, 1, 2 and 6 weeks of product use.ResultsIn total, 110 participants were screened for study entry and all were randomized to receive one of three toothpastes (experimental: sodium hyaluronate, sodium bicarbonate, sodium fluoride; positive control: sodium bicarbonate, sodium fluoride; negative control: regular fluoride toothpaste). For all measures, significant improvements were observed in participants receiving either sodium bicarbonate-containing toothpaste (experimental or positive control) compared with the regular fluoride toothpaste (negative control) at week 6. No significant difference was observed in any assessment or visit comparing the experimental toothpaste with the positive control.ConclusionsBoth the experimental and the positive control toothpastes demonstrated clinically relevant improvements in gingival health compared with a regular fluoride toothpaste (negative control). However, no additional gingival health improvement was observed for the experimental toothpaste compared with the positive control, therefore, no additional gingival health benefit can be attributed to the inclusion of sodium hyaluronate in this formulation.Trial registrationClinicalTrials.gov Identifier: NCT04737538 (04/02/2021).

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Modified toothpaste application using prepared toothpaste delivering technique increases interproximal fluoride toothpaste delivery.

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Modified toothpaste application using prepared toothpaste delivering technique increases interproximal fluoride toothpaste delivery.

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