Ontology highlight
ABSTRACT:
SUBMITTER: Gilad A
PROVIDER: S-EPMC7142160 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Gilad Ariel A Helmchen Fritjof F
Nature communications 20200408 1
Association areas in neocortex encode novel stimulus-outcome relationships, but the principles of their engagement during task learning remain elusive. Using chronic wide-field calcium imaging, we reveal two phases of spatiotemporal refinement of layer 2/3 cortical activity in mice learning whisker-based texture discrimination in the dark. Even before mice reach learning threshold, association cortex-including rostro-lateral (RL), posteromedial (PM), and retrosplenial dorsal (RD) areas-is genera ...[more]