Ontology highlight
ABSTRACT:
SUBMITTER: Martynowycz MW
PROVIDER: S-EPMC7145226 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Structure (London, England : 1993) 20190815 10
Microcrystal electron diffraction (MicroED) leverages the strong interaction between matter and electrons to determine protein structures from vanishingly small crystals. This strong interaction limits the thickness of crystals that can be investigated by MicroED, mainly due to absorption. Recent studies have demonstrated that focused ion-beam (FIB) milling can thin crystals into ideal-sized lamellae; however, it is not clear how to best apply FIB milling for MicroED. Here, the effects of polish ...[more]