Ontology highlight
ABSTRACT:
SUBMITTER: Zhao Y
PROVIDER: S-EPMC7146974 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Zhao Yanchun Y Shi Yuanfei Y Shen Huafei H Xie Wanzhuo W
Journal of hematology & oncology 20200410 1
N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is a well-known post-transcriptional modification that is the most common type of methylation in eukaryotic mRNAs. The regulation of m<sup>6</sup>A is dynamic and reversible, which is erected by m<sup>6</sup>A methyltransferases ("writers") and removed by m<sup>6</sup>A demethylases ("erasers"). Notably, the effects on targeted mRNAs resulted by m<sup>6</sup>A predominantly depend on the functions of different m<sup>6</sup>A-binding proteins ("reade ...[more]