Ontology highlight
ABSTRACT:
SUBMITTER: Azuma Y
PROVIDER: S-EPMC7154120 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Azuma Yoshihiro Y Suzuki Yasuo Y Okada Seigo S Matsuguma Chie C Wakiguchi Hiroyuki H Ohnishi Yuji Y Furuta Takashi T Miyake Akiko A Yasudo Hiroki H Ichihara Kiyoshi K Ohga Shouichi S Hasegawa Shunji S
Frontiers in pediatrics 20200407
<b>Objective:</b> Intravenous immunoglobulin (IVIG) therapy is a useful first-line treatment for Kawasaki disease (KD); however, 10-20% of patients fail to respond and require additional IVIG. Soluble CD163 (sCD163) is considered a biomarker for macrophage activation. There are no reports measuring serum sCD163 in KD patients. This study aimed to explore its possible utility in the clinical management of patients with KD. <b>Methods:</b> Eighty-seven patients with well-defined KD were retrospect ...[more]