From Interaction to Function in DNA-Templated Supramolecular Self-Assemblies.

ABSTRACT: DNA-templated self-assembly represents a rich and growing subset of supramolecular chemistry where functional self-assemblies are programmed in a versatile manner using nucleic acids as readily-available and readily-tunable templates. In this review, we summarize the different DNA recognition modes and the basic supramolecular interactions at play in this context. We discuss the recent results that report the DNA-templated self-assembly of small molecules into complex yet precise nanoarrays, going from 1D to 3D architectures. Finally, we show their emerging functions as photonic/electronic nanowires, sensors, gene delivery vectors, and supramolecular catalysts, and their growing applications in a wide range of area from materials to biological sciences.

SUBMITTER: Surin M 

PROVIDER: S-EPMC7175023 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature