Ontology highlight
ABSTRACT:
SUBMITTER: Saari H
PROVIDER: S-EPMC7178890 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Saari Heikki H Turunen Tiia T Lõhmus Andres A Turunen Mikko M Jalasvuori Matti M Butcher Sarah J SJ Ylä-Herttuala Seppo S Viitala Tapani T Cerullo Vincenzo V Siljander Pia R M PRM Yliperttula Marjo M
Journal of extracellular vesicles 20200417 1
Extracellular vesicles (EVs) have been showcased as auspicious candidates for delivering therapeutic cargo, including oncolytic viruses for cancer treatment. Delivery of oncolytic viruses in EVs could provide considerable advantages, hiding the viruses from the immune system and providing alternative entry pathways into cancer cells. Here we describe the formation and viral cargo of EVs secreted by cancer cells infected with an oncolytic adenovirus (IEVs, infected cell-derived EVs) as a function ...[more]