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An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report.


ABSTRACT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal-oral transmission for COVID-19.

SUBMITTER: Li J 

PROVIDER: S-EPMC7200387 | biostudies-literature | 2020 May - Jun

REPOSITORIES: biostudies-literature

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An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report.

Li Juan J   Feng Jing J   Liu Tian-Hu TH   Xu Feng-Cheng FC   Song Guo-Qiang GQ  

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20200506 3


Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persiste  ...[more]

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