Ontology highlight
ABSTRACT:
SUBMITTER: Chen AJ
PROVIDER: S-EPMC7216751 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Chen Andy J AJ Li Junjie J Jannasch Amber A Mutlu Ayse Sena AS Wang Meng C MC Cheng Ji-Xin JX
Chemphyschem : a European journal of chemical physics and physical chemistry 20180723 19
Retinoids play critical roles in development, immunity, and lipid metabolism, and their deficiency leads to various human disorders. Yet, tools for sensing retinoids in vivo are lacking, which limits the understanding of retinoid distribution, dynamics and functions in living organisms. Here, using hyperspectral stimulated Raman scattering microscopy, we discover a previously unknown cytoplasmic store of retinoids in Caenorahbditis elegans. Following the temporal dynamics of retinoids, we reveal ...[more]