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Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension.


ABSTRACT: PURPOSE:Ascent to high altitude increases right ventricular (RV) afterload and decreases myocardial energy supply. This study evaluates physiologic variables and comprehensive echocardiographic indices of RV and right atrial (RA) function following rapid ascent to high altitude. METHODS:Fifty healthy volunteers actively ascended from 1130 to 4559 m in?

SUBMITTER: Sareban M 

PROVIDER: S-EPMC7228961 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension.

Sareban Mahdi M   Perz Tabea T   Macholz Franziska F   Reich Bernhard B   Schmidt Peter P   Fried Sebastian S   Mairbäurl Heimo H   Berger Marc M MM   Niebauer Josef J  

The international journal of cardiovascular imaging 20200309 6


<h4>Purpose</h4>Ascent to high altitude increases right ventricular (RV) afterload and decreases myocardial energy supply. This study evaluates physiologic variables and comprehensive echocardiographic indices of RV and right atrial (RA) function following rapid ascent to high altitude.<h4>Methods</h4>Fifty healthy volunteers actively ascended from 1130 to 4559 m in < 22 h. All participants underwent 2D echocardiography during baseline examination at low altitude (424 m) and at three study time-  ...[more]

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