ABSTRACT: Species of the spider family Telemidae Fage, 1913 from East and Southeast Asia are revised. Four new genera are erected: Mekonglema Zhao & Li, gen. nov. with the type species Mekonglema bailang Zhao & Li, sp. nov. (??, Yunnan, China), Siamlema Zhao & Li, gen. nov. with the type species Siamlema changhai Zhao & Li, sp. nov. (??, southern Thailand), Sundalema Zhao & Li, gen. nov. with the type species Sundalema bonjol Zhao & Li, sp. nov. (??, Sumatra), and Zhuanlema Zhao & Li, gen. nov. with the type species Zhuanlema peteri Zhao & Li, sp. nov. (??, northern Laos). Eight additional new species are described: Mekonglema kaorao Zhao & Li, sp. nov. (??, northern Laos), M. walayaku Zhao & Li, sp. nov. (??, Yunnan, China), M. yan Zhao & Li, sp. nov. (??, Yunnan, China), Pinelema daguaiwan Zhao & Li, sp. nov. (??, Guangxi, China), P. shiba Zhao & Li, sp. nov. (??, Guangxi, China), P. tham Zhao & Li, sp. nov. (??, northern Laos), Siamlema suea Zhao & Li, sp. nov. (??, southern Thailand), and Sundalema khaorakkiat Zhao & Li, sp. nov. (??, southern Thailand). Thirty species are transferred from the genus Telema Simon, 1882 to the genera Pinelema Wang & Li, 2012, Sundalema gen. nov., and Telemofila Wunderlich, 1995. Seychellia xinpingi Lin & Li, 2008 is transferred to Mekonglema gen. nov. as M. xinpingi comb. nov. Furthermore, the genus Pinelema is divided into seven species groups based on male morphological characters.