Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC7250629 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Nature chemistry 20200120 2
Meroterpenoids are natural products of hybrid biosynthetic origins-derived from both terpenoid and polyketide pathways-with a wealth of biological activities. Given their therapeutic potential, a general strategy to access these natural products in a concise and divergent fashion is highly desirable. Here, we report a modular synthesis of a suite of oxidized meroterpenoids using a hybrid synthetic strategy that is designed to harness the power of both biocatalytic and radical-based retrosyntheti ...[more]