Ontology highlight
ABSTRACT:
SUBMITTER: Flitsch LJ
PROVIDER: S-EPMC7251072 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Flitsch Lea J LJ Laupman Karen E KE Brüstle Oliver O
Frontiers in cellular neuroscience 20200520
Traditionally, <i>in vitro</i> generation of donor cells for brain repair has been dominated by the application of extrinsic growth factors and morphogens. Recent advances in cell engineering strategies such as reprogramming of somatic cells into induced pluripotent stem cells and direct cell fate conversion have impressively demonstrated the feasibility to manipulate cell identities by the overexpression of cell fate-determining transcription factors. These strategies are now increasingly imple ...[more]