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Associations of childhood adiposity with menstrual irregularity and polycystic ovary syndrome in adulthood: the Childhood Determinants of Adult Health Study and the Bogalusa Heart Study.


ABSTRACT:

SUBMITTER: He Y 

PROVIDER: S-EPMC7259370 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Associations of childhood adiposity with menstrual irregularity and polycystic ovary syndrome in adulthood: the Childhood Determinants of Adult Health Study and the Bogalusa Heart Study.

He Y Y   Tian J J   Blizzard L L   Oddy W H WH   Dwyer T T   Bazzano L A LA   Hickey M M   Harville E W EW   Venn A J AJ  

Human reproduction (Oxford, England) 20200501 5


<h4>Study question</h4>Is high adiposity in childhood associated with menstrual irregularity and polycystic ovary syndrome (PCOS) in later life?<h4>Summary answer</h4>Overall, greater childhood BMI was associated with menstrual irregularity, and greater childhood BMI and waist/height ratio (WHtR) in white but not black participants were associated with PCOS in adulthood.<h4>What is known already</h4>Increased childhood BMI has been associated with irregular menstrual cycles and PCOS symptoms in  ...[more]

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