Ontology highlight
ABSTRACT:
SUBMITTER: Wang P
PROVIDER: S-EPMC7261494 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Wang Pengfei P Rahman Mohammad Aminur MA Zhao Zhixiang Z Weiss Kristin K Zhang Chao C Chen Zhengjia Z Hurwitz Selwyn J SJ Chen Zhuo G ZG Shin Dong M DM Ke Yonggang Y
Journal of the American Chemical Society 20180212 7
DNA origami is a promising molecular delivery system for a variety of therapeutic applications including cancer therapy, given its capability to fabricate homogeneous nanostructures whose physicochemical properties (size, shape, surface chemistry) can be precisely tailored. However, the correlation between DNA-origami design and internalization efficiency in different cancer cell lines remains elusive. We investigated the cellular uptake of four DNA-origami nanostructures (DONs) with programmed ...[more]