Ontology highlight
ABSTRACT:
SUBMITTER: Lee J
PROVIDER: S-EPMC7271767 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Cell reports 20200501 5
The eight metabotropic glutamate receptors (mGluRs) serve critical modulatory roles throughout the nervous system. The molecular diversity of mGluRs is thought to be further expanded by the formation of heterodimers, but the co-expression of mGluR subtypes at the cellular level and the relative propensities of heterodimer formation are not well known. Here, we analyze single-cell RNA sequencing data and find that cortical pyramidal cells express multiple mGluR subtypes with distinct profiles for ...[more]