Modeling the temporal network dynamics of neuronal cultures.
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ABSTRACT:
SUBMITTER: Cadena J
PROVIDER: S-EPMC7274455 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Modeling the temporal network dynamics of neuronal cultures.
Cadena Jose J Sales Ana Paula AP Lam Doris D Enright Heather A HA Wheeler Elizabeth K EK Fischer Nicholas O NO
PLoS computational biology 20200526 5
Neurons form complex networks that evolve over multiple time scales. In order to thoroughly characterize these networks, time dependencies must be explicitly modeled. Here, we present a statistical model that captures both the underlying structural and temporal dynamics of neuronal networks. Our model combines the class of Stochastic Block Models for community formation with Gaussian processes to model changes in the community structure as a smooth function of time. We validate our model on synt ...[more]
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