Ontology highlight
ABSTRACT:
SUBMITTER: Morris DR
PROVIDER: S-EPMC7279010 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Morris Dorothea R DR Bounds Sarah E SE Liu Huanhuan H Ding Wei-Qun WQ Chen Yan Y Liu Yin Y Cai Jiyang J
International journal of molecular sciences 20200517 10
The retinal pigment epithelium (RPE), the outermost layer of the retina, provides essential support to both the neural retina and choroid. Additionally, the RPE is highly active in modulating functions of immune cells such as microglia, which migrate to the subretinal compartment during aging and age-related degeneration. Recently, studies have highlighted the important roles of microRNA (miRNA) in the coordination of general tissue maintenance as well as in chronic inflammatory conditions. In t ...[more]