Ontology highlight
ABSTRACT:
SUBMITTER: Van Bibber NW
PROVIDER: S-EPMC7279152 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Van Bibber Nathan W NW Haerle Cornelia C Khalife Roy R Xue Bin B Uversky Vladimir N VN
International journal of molecular sciences 20200525 10
Among the realm of repeat containing proteins that commonly serve as "scaffolds" promoting protein-protein interactions, there is a family of proteins containing between 2 and 20 tetratricopeptide repeats (TPRs), which are functional motifs consisting of 34 amino acids. The most distinguishing feature of TPR domains is their ability to stack continuously one upon the other, with these stacked repeats being able to affect interaction with binding partners either sequentially or in combination. It ...[more]