Ontology highlight
ABSTRACT:
SUBMITTER: Xu Y
PROVIDER: S-EPMC4393279 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Xu Yanan Y Cao Jingli J Huang Shan S Feng Di D Zhang Wei W Zhu Xueliang X Yan Xiumin X
PloS one 20150410 4
Cilia formation and function require a special set of trafficking machinery termed intraflagellar transport (IFT), consisting mainly of protein complexes IFT-A, IFT-B, BBSome, and microtubule-dependent molecular motors. Tetratricopeptide repeat-containing (TTC) proteins are widely involved in protein complex formation. Nine of them are known to serve as components of the IFT or BBSome complexes. How many TTC proteins are cilia-related and how they function, however, remain unclear. Here we show ...[more]