The Role of Toll-like Receptors in Atherothrombotic Cardiovascular Disease.
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ABSTRACT:
SUBMITTER: Zhou Y
PROVIDER: S-EPMC7296543 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
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The Role of Toll-like Receptors in Atherothrombotic Cardiovascular Disease.
Zhou Ying Y Little Peter J PJ Downey Liam L Afroz Rizwana R Wu Yuao Y Ta Hang T HT Xu Suowen S Kamato Danielle D
ACS pharmacology & translational science 20200206 3
Toll-like receptors (TLRs) are dominant components of the innate immune system. Activated by both pathogen-associated molecular patterns and damage-associated molecular patterns, TLRs underpin the pathology of numerous inflammation related diseases that include not only immune diseases, but also cardiovascular disease (CVD), diabetes, obesity, and cancers. Growing evidence has demonstrated that TLRs are involved in multiple cardiovascular pathophysiologies, such as atherosclerosis and hypertensi ...[more]
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