Ontology highlight
ABSTRACT:
SUBMITTER: Browne EP
PROVIDER: S-EPMC7697840 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Microorganisms 20201114 11
Toll-like receptors (TLRs) are key pathogen sensing receptors that respond to diverse microbial ligands, and trigger both innate and adaptive immune responses to infection. Since their discovery, a growing body of evidence has pointed to an important role for TLRs in retroviral infection and pathogenesis. These data suggest that multiple TLRs contribute to the anti-retroviral response, and that TLR engagement by retroviruses can have complex and divergent outcomes for infection. Despite this pro ...[more]