Dataset Information

Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography.

ABSTRACT:

Background

To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops.

Methods

Anterior segment optical coherence tomography (AS-OCT) images of the bulbar conjunctiva of 328 eyes were analyzed with and without anti-glaucoma eye drops to quantify the preservation rates of the conjunctival layer borderlines.

Results

More anti-glaucoma eye drops and a longer duration of administration were associated with lower preservation rates of the borderlines between both the conjunctival stroma/Tenon's capsule (P < 0.001 and P < 0.001, respectively) and Tenon's capsule/sclera (P < 0.001 and P < 0.001, respectively). Prostaglandin analogs and fixed combinations of β-blockers/prostaglandin analogs were prognostic factors for lower preservation rates of the borderlines between both the conjunctival stroma/Tenon's capsule (P < 0.001 and P = 0.009, respectively) and Tenon's capsule/sclera (P < 0.001 and P = 0.008, respectively).

Conclusions

Numerous anti-glaucoma eye drops and their long-term administration are associated with the disruption of the bulbar conjunctival borderlines detected by AS-OCT.

SUBMITTER: Gozawa M

PROVIDER: S-EPMC7304144 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Publications

Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography.

Gozawa Makoto M Takamura Yoshihiro Y Iwasaki Kentaro K Arimura Shogo S Inatani Masaru M

BMC ophthalmology 20200619 1

<h4>Background</h4>To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops.<h4>Methods</h4>Anterior segment optical coherence tomography (AS-OCT) images of the bulbar conjunctiva of 328 eyes were analyzed with and without anti-glaucoma eye drops to quantify the preservation rates of the conjunctival layer borderlines.<h4>Results</h4>More anti-glaucoma eye drops and a longer duration of adm ...[more]

PMID: 32560643

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Project description:In the past 20 years, the research application of anterior segment optical coherence tomography (AS-OCT) in the field of glaucoma has become a hot topic, but there is still a lack of bibliometric reports on this scientific field. The aim of this study is to explore the research hotspots and trends in the field using bibliometric methods. Analyzing literature from 2004 to 2023 on AS-OCT in glaucoma within the SCI database, this study utilized Bibliometric, VOS viewer, and Cite Space for a comprehensive bibliometric analysis covering document counts, countries, institutions, journals, authors, references, and keywords. A total of 931 eligible articles were collected, showing a continuous increase in annual research output over the past 20 years. The United States, China, and Singapore were the top three countries in terms of publication volume, with 288, 231, and 124 articles, respectively, and there was close cooperation among these countries. The NATIONAL UNIVERSITY OF SINGAPORE, SUN YAT SEN UNIVERSITY, and SINGAPORE NATIONAL EYE CENTRE were the most productive institutions with 93, 92, and 87 articles, respectively. JOURNAL OF GLAUCOMA, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, and OPHTHALMOLOGY were the journals with the highest number of publications, with 86, 69, and 46 articles, respectively. PROGRESS IN RETINAL AND EYE RESEARCH, published in the United States, was the top-cited journal. Researchers Aung Tin, He Mingguang, and David S. Friedman were highlighted for their contributions. The reference clustering was divided into 12 categories, among which "deep learning, anterior segment" were the most cited categories. The keywords of research frontiers include deep learning, classification, progression, and management. This article analyses the academic publications on AS-OCT in the diagnosis and treatment of glaucoma over the last 20 years. Among them, the United States contributed the largest number of publications in this field, with the highest number of literature citations and mediated centrality. Among the prolific authors, aung, tin topped the list with 77 publications and 3,428 citations. Since the beginning of 2018, advances in artificial intelligence have shifted the focus of research in this field from manual measurements to automated detection and identification of relevant indicators.

Dataset Information

Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography.

Background

Methods

Results

Conclusions

Publications

Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography.

Similar Datasets

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