Ontology highlight
ABSTRACT:
SUBMITTER: Grof I
PROVIDER: S-EPMC7312297 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Gróf Ilona I Bocsik Alexandra A Harazin András A Santa-Maria Ana Raquel AR Vizsnyiczai Gaszton G Barna Lilla L Kiss Lóránd L Fűr Gabriella G Rakonczay Zoltán Z Ambrus Rita R Szabó-Révész Piroska P Gosselet Fabien F Jaikumpun Pongsiri P Szabó Hajnalka H Zsembery Ákos Á Deli Mária A MA
International journal of molecular sciences 20200604 11
Clinical and experimental results with inhaled sodium bicarbonate as an adjuvant therapy in cystic fibrosis (CF) are promising due to its mucolytic and bacteriostatic properties, but its direct effect has not been studied on respiratory epithelial cells. Our aim was to establish and characterize co-culture models of human CF bronchial epithelial (CFBE) cell lines expressing a wild-type (WT) or mutant (deltaF508) CF transmembrane conductance regulator (CFTR) channel with human vascular endothelia ...[more]